If you are still getting that many and sometimes more, I would suggest exactly what I did to OP in another comment. Get a new number. Grab one from GV, number barn, etc that hasn’t been used in awhile. Alternatively move your current number (if you want to keep it long term) and get a new direct number.
I have my main number on GV, I’ve had it for over a decade. I ported it to GV from tmo about that long ago. I grew up in Florida so just because I got a 727 area code for my personal direct line, I moved that sim to my work phone when I moves to having 2 phones. That number gets like 5 calls a week if that and they are mostly from house flippers trying to lowball me on a property I don’t own nor have ever seen. The other ones are political bs. My current personal direct line is a local number and that one gets literally zero spam calls, a few texts but nowhere near the insanity that some people deal with. I have no idea how many calls or texts are being blocked by tmo now.
I’ll repeat. If you are getting a shit storm of spam and turning on the carrier level protection doesn’t help, it’s time for a new number. I responded up top level because OP was being obstinate and saying that a new number was pointless because it had been used by deadbeats (paraphrasing here) without seeing the irony in that statement.
I don’t have that level of protection turned on and I get very few calls. Both my work and personal numbers are on GV so if somehow either of my direct lines start getting spam bombed I can burn them and get new ones. Thinking about it, I should maybe be prepared and grab one to park as I’ve advised so I have a fresh and clean one ready to go.