Seinfeld- Jerry and Elaine are exes and breify get back together at the end of season one
Friends- lots of romantic entaglements but mainly Chandler/Monica, Ross/Rachel, and Joey/Rachel
How I Met Your Mother - two of the main characters are a steady couple, the other three are a love triangle
Big Bang Theory- by the end, it’s three couples and one single guy
Any shows like these where the main characters never date each other or hook up with each other?
Only Murders in the Building I agree on but Abbott Elementary has romance between Gregory and Janine. The Orville has romance between Isaac and Claire and arguably Ed and Kelly (exes who seem to still have feelings for eachother) I can’t comment on your other examples, I haven’t seen them
OPs examples have one couple but still other friends.